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Today on Medscape : Get the latest medical news, clinical trial coverage, drug updates, journal articles, CME activities & more on Medscape. A free resource for physicians.
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#MentalHealth #CrisisSupport #SuicidePrevention
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Young Adults With Suicidal Ideation: Who Reaches Out by Texting for Help and Why Do Others Hold Back?
Among young adults with suicidal ideation, factors associated with the use of crisis text services were female sex, minoritized sexual orientation, engagement with a mental health provider, and prior hospitalizations.
#COVID19 #Pregnancy #AntiviralTreatment
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Why Are Pregnant Patients With COVID-19 Less Likely to Receive Antiviral Treatment?
Among pregnant patients diagnosed with COVID-19, only 6. 7% received ritonavir-boosted nirmatrelvir (NMV/r) treatment compared with 43% of those with influenza who received oseltamivir.
#MedicalResidency #MaternityLeave #WomenInMedicine
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Former Ob/Gyn Resident Wins $10M in Maternity Leave Lawsuit
A former Michigan medical resident was awarded more than $10 million by a federal jury this week after alleging she was terminated from her obstetrics and gynecology residency for failing a licensing exam she was required to take during job-protected maternity leave.
#PlasticWaste #ParkinsonsDisease #SyntheticBiology
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Waste Not, Want Not: Scientists Turn Plastic Into Levodopa for Parkinson's Disease
In a scientific first, researchers have turned plastic waste into a mainstay treatment for Parkinson's disease (PD).
In a proof-of-concept study, researchers used engineered bacteria to convert polyethylene terephthalate (PET) -- a widely used plastic found in bottles and food packaging -- into levodopa (L-DOPA).
#DiabetesRisk #HealthInnovation #PreventiveMedicine
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Brazilian 10-Year Diabetes Risk Calculator
What is a person's risk of developing diabetes in 10 years. A tool created by researchers at the Federal University of Rio Grande do Sul, Porto Alegre, Brazil; the Federal University of Espírito Santo, Vitória, Brazil; the Federal University of Minas Gerais, Belo Horizonte, Brazil; and the Oswaldo Cruz Foundation, Rio de Janeiro, Brazil, aims to answer that question.
#Psychedelics #DepressionTreatment #ClinicalResearch
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Mixed Results for Psilocybin as Blinding Concerns Remain
Two new major studies tackle what many researchers believe to be the central unresolved issue in the assessment of psychedelics as treatment for depression: Whether the apparent benefits are inflated by failures of blinding.
#Epilepsy #MentalHealth #Suicidality
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Suicidality May Predict Treatment Resistance in Newly Diagnosed Focal Epilepsy
Suicidality at the time of a focal epilepsy diagnosis was associated with a higher risk for future treatment resistance to antiseizure medications (ASMs), independent of concurrent mood or anxiety disorders, a recent cohort study showed.
#3DPrinting #BiomedicalEngineering #MedicalInnovation
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Lifelike 3D-Printed 'Training Brains' React Like Real Organs
Imagine what brain surgeons could do with a three-dimensional (3D)-printed model of the brain. Not a structural model printed in plastic and uniform throughout, but one that mirrors the heterogeneity of real human brain tissue -- its mechanical, thermal, and electromagnetic properties.
#COVID19 #Vaccination #Pregnancy
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COVID Vaccination in Pregnancy Protect Infants' First 6 Months
COVID vaccination during pregnancy protects infants from hospitalization during their first 6 months of life.
Published in Pediatrics, the study offers valuable insights for clinicians engaging in discussions with pregnant patients about the benefits of vaccination.
#PsychotropicMedications #BoneHealth #MentalHealth
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Psychotropic Drug Use Linked to Bone Loss in Men
Use of psychotropic medications, particularly selective serotonin reuptake inhibitors (SSRIs) and anticonvulsants, was associated with bone loss at the spine and hip in men with lower BMI, a new cohort study showed.
#HidradenitisSuppurativa #CancerRisk #MetaAnalysis
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Hidradenitis Suppurativa Associated With Elevated Risks for Multiple Cancer Types
In a meta-analysis, patients with hidradenitis suppurativa (HS) faced a more than 80% higher risk for cancer overall than the general population, with particularly elevated risks for gastrointestinal, head and neck, haematologic, and respiratory system cancers.
#Healthcare #WorkplaceCulture #PatientCommunication
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'I HATE YOU' and Other Things People Say to Their Doctors
The angry portal message arrives at 9:47 PM. The clinician is home, maybe halfway through dinner, and there it is: A patient who was pleasant enough in the exam room that afternoon, now typing things they would never say to anyone's face.
#HepatitisC #HIV #PublicHealth
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Drop in HIV/HCV Coinfections After Nationwide HCV Program
During the nationwide hepatitis C elimination program in Iceland, the number of HIV/hepatitis C virus (HCV) coinfections reduced by more than 85% from 2016 to 2020, primarily due to the widespread use of direct-acting antivirals (DAAs).
#AdolescentWellbeing #SocialInequality #RelativeDeprivation
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Relative Deprivation Affects Adolescent Health, Well-Being
MONTREAL -- Adolescent well-being is influenced not only by the amount of socioeconomic deprivation young people face but also by the amount of deprivation relative to others in their sphere of influence, according to presentations at Public Health 2026, the annual meeting of the Canadian Public Health Association.
#PrenatalExposure #AntiseizureMedications #NeurodevelopmentalDisorders
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Prenatal Antiseizure Med Exposure: Risks Vary by Agent
Prenatal exposure to certain antiseizure medications (ASMs) was associated with an increased risk for neurodevelopmental disorders (NDDs) in children, with risk varying by individual drug.
#Diabetes #Hypertension #CardiovascularHealth
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Early Hypertension Linked to a Poorer Prognosis in T2D
In patients with type 2 diabetes (T2D), both young-onset hypertension (onset before the age of 45 years) and late-onset hypertension (onset at the age of 45 years or later) were associated with higher risks for cardiovascular disease (CVD), congestive heart failure, chronic kidney disease, and all-cause mortality, with young-onset hypertension linked to poorer outcomes.
#Diabetes #Hypertension #CardiovascularHealth
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Early Hypertension Linked to a Poorer Prognosis in T2D
In patients with type 2 diabetes (T2D), both young-onset hypertension (onset before the age of 45 years) and late-onset hypertension (onset at the age of 45 years or later) were associated with higher risks for cardiovascular disease (CVD), congestive heart failure, chronic kidney disease, and all-cause mortality, with young-onset hypertension linked to poorer outcomes.
#UlcerativeColitis #ColorectalCancer #MucosalInflammation
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Ulcerative Colitis With Background Mucosal Inflammation Signals Poor Survival in Colorectal Cancer
Among patients with ulcerative colitis (UC) who develop colorectal cancer (CRC), greater background mucosal inflammation at the time of CRC diagnosis is associated with progressively worse survival outcomes, with tumors arising within the UC‑involved segment having worse prognosis.
#VeteransHealth #VirtualCare #EmergencyDepartment
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Virtual Care Expansion in VA Health System Tied to 12% Drop in ED Visits for Low-Acuity Conditions
Emergency department (ED) visits by veterans for low‑acuity conditions declined following the Veterans Affairs (VA) virtual care expansion in March 2020 and remained 12% below the baseline rate through February 2023.
#VeteransHealth #VirtualCare #EmergencyDepartment
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Virtual Care Expansion in VA Health System Tied to 12% Drop in ED Visits for Low-Acuity Conditions
Emergency department (ED) visits by veterans for low‑acuity conditions declined following the Veterans Affairs (VA) virtual care expansion in March 2020 and remained 12% below the baseline rate through February 2023.
#HepatocellularCarcinoma #Radiotherapy #TACE
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Adding Radiotherapy to TACE May Improve Early HCC Survival
In a comparative study, the early addition of radiotherapy to transarterial chemoembolization (TACE) was associated with improved 5-year overall survival and progression-free survival compared with TACE alone among patients with early-stage hepatocellular carcinoma (HCC).
#HepatocellularCarcinoma #Radiotherapy #TACE
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Adding Radiotherapy to TACE May Improve Early HCC Survival
In a comparative study, the early addition of radiotherapy to transarterial chemoembolization (TACE) was associated with improved 5-year overall survival and progression-free survival compared with TACE alone among patients with early-stage hepatocellular carcinoma (HCC).
#Tuberculosis #ClinicalTrial #Rifampin
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High-Dose Rifampin Fails to Improve TB Meningitis Survival
High-dose rifampin -- 35 mg/kg daily -- administered for 8 weeks showed no reduction in mortality rate compared with standard-dose rifampin -- 10 mg/kg daily -- in patients with tuberculous meningitis but was accompanied by more early deaths and slower normalization of mental status.
#Tuberculosis #ClinicalTrial #Rifampin
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High-Dose Rifampin Fails to Improve TB Meningitis Survival
High-dose rifampin -- 35 mg/kg daily -- administered for 8 weeks showed no reduction in mortality rate compared with standard-dose rifampin -- 10 mg/kg daily -- in patients with tuberculous meningitis but was accompanied by more early deaths and slower normalization of mental status.
#GeneEditing #BetaThalassemia #HealthcareInnovation
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Gene-Editing Breakthrough Ends Transfusions for UK Patient
The first successful gene-editing treatment for beta thalassaemia has been delivered at University College London Hospital (UCLH), marking a milestone for patients with the inherited blood disorder.
